Biogenic Nano-Synthesis; towards the Efficient Production of the Biocompatible Gold Nanoparticles

Bulletin of the Korean chemical society

Si Wouk Kim¹  EonSeon Jin¹  Gajanan Ghodake¹  Chi Yong Eom¹ 

关键词: Biogenic;    AuNPs;    Cell viability assay;    Nontoxic green product;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

We present a rapid biogenic method for the production of nanoscale gold particles using pear extract. The formation and stability of pear-derived gold nanoparticles (Pear-AuNPs) were monitored by ultraviolet-visible spectroscopy. Their morphology, elemental composition and crystalline phase were determined by transmission electron microscopy, energydispersive X-ray spectroscopy and selected area electron diffraction. The average core size of crystalline Pear-AuNPs was in the range of 10 �? 5 nm and the observed morphology was spherical. The X-ray photoelectron spectrum showed a strong peak for the pure ‘Au�? phase. The circular dichroism spectrum indicated the natural capping ability of the pear extract, which generated peptide-gold nanoparticles. These nanoparticles were stable in aqueous solution for two months. A cell viability assay of Pear-AuNPs showed biocompatibility with human embryonic kidney 293 cells. Accordingly, this eco-friendly process for the bio-mimetic production of Pear-AuNPs is nontoxic in nature; consequently, it will find potential application in nano-biotechnology.

【 授权许可】

Unknown