Synthesis of Poly(benzyl ether) Dendrimers Containing Core Diversities by Click Chemistry

Bulletin of the Korean chemical society

Jae Wook Lee¹  Byoung Ki Kim¹  Ji Hyeon Kim¹  Seung Choul Han¹ 

关键词: Alkyne;    Azide;    Click chemistry;    Frechet-type dendrimers;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

General, fast, and efficient methods for the synthesis of Frechet-type dendrimers having core diversities were elaborated. Two core building blocks, 4,4`-(3,5-bis(propargyloxy)benzyloxy)bisphenyl and N,N,N`,N`-tetra(prop-2- ynyloxycarbonylethyl)-1,2-diaminoethane, were designed to serve as the alkyne functionalities for dendrimer growth via click reactions with the azide-dendrons. The synthetic strategy involved an 1,3-dipolar cycloaddition reaction between an alkyne and an azide- functionalized Frechet-type dendrons in the presence of Cu(I) species which is known as the best example of click chemistry.

【 授权许可】

Unknown