Analysis of Chemical Warfare Agents in Water Using Single-Drop Microextraction

Bulletin of the Korean chemical society

Sung Ki Kim¹  Ju Sub Park¹  Hong Ku Kang¹  Kihwan Choi¹  Byung Hoon Son¹  Yang Gi Park¹ 

关键词: Single-drop microextraction;    Chemical warfare agents;    Nerve agents;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Single-drop microextraction (SDME) is an extraction methodology where the drop plays an essential role as extracts. It was evaluated for the GC-MS determination of nerve agents, one class of the chemical warfare agents (CWAs). Since these nerve agents are highly toxic, it is important to detect the nerve agents in the environmental samples. Several affecting factors including extraction solvents, stirring rate, extraction time, and amounts of salt were optimized. The limit of detections (LODs) were 0.1 - 10 ng/mL and the relative standard deviations (RSDs%, n=5) were in the range of 6.3% to 9.0% for four nerve agents. Without pretreatment of the environmental samples, 5-103 fold enrichments and 48-100% recovery were accomplished. These results demonstrated the feasibility of this method for on-site and off-site analysis of water sample collected from suspicious CWAs site.

【 授权许可】

Unknown