Facile One-Pot Two-Step Hydroxylation of Alkyl Halides and Alkyl Sulfonates via Acetate Intermediates

Bulletin of the Korean chemical society

Keun Sam Jang¹  Dae Yoon Chi¹  Jae Hak Lee¹  Uthaiwan Sirion¹  Byoung Se Lee¹ 

关键词: Acetoxylation;    One-pot two-step hydroxylation;    Alkyl halides;    Alkyl sulfonate;    Alkyl acetate;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Hydroxylation of primary and secondary alkyl halides and alkyl sulfonates was readily achieved by one-pot two-step reaction under mild condition. Less reactive chloride and secondary mesylate functionalities were also transformed to hydroxide group in high yields. When 5% water-containing DMSO solvent was used, catalytic cycle of two-step hydroxylation smoothly proceeded in the presence of catalytic amount of acetate anion.

【 授权许可】

Unknown