Lactonization of ¥ø-Hydroxycarboxylic Acids Using (4,5-Dichloro-6-oxo-6H-pyridazin-1-yl)phosphoric Acid Diethyl Ester

Bulletin of the Korean chemical society

Sang Gyeong Lee¹  Kwang Ju Jung¹  Jeum Jong Kim¹  Ju Eun Won¹  Seung Beom Kang¹  Min Jung Kim¹  Yong Jin Yoon¹  Song Eun Park¹ 

关键词: Lactonization;    �?-Hydroxycarboxylic acid;    (6-Oxo-6H-pyridazin-1-yl)phosphoric acid diethylester;    Lactone;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

(4,5-Dichloro-6-oxo-6H-pyridazin-1-yl)phosphoric acid diethyl ester (3) is an efficient coupling agent for lactonization of aliphatic and aromatic �?-hydroxycarboxylic acids. Lactonization of �?-hydroxycarboxylic acids with 3 in the presence of equimolar amounts of a base gave the corresponding monoolides, diolides, triolides and/or tetraolides.

【 授权许可】

Unknown