Approaches to the Syntheses of Partially Reduced Imidazo[1,2-a]pyridines

Bulletin of the Korean chemical society

Young Chang Nho¹  Arthur S Howard¹  Junhwa Shin¹ 

关键词: Aza-alkaloid;    Heterocyclic compounds;    Indolizidine;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Two synthetic pathways to substituted hexahydroimidazo[1,2-a]pyridines, which may serve as precursors of aza-alkaloids, were investigated. The first involves the condensation of a bisnucleophilic enediaminoester and a biselectrophile. The second involves attachment to nitrogen of the carbon chain skeleton required to form the six-memberd ring, before formation of the enediaminoester. Several substituted hexahydroimidazo[1,2- a]pyridines were synthesized via these two approaches.

【 授权许可】

Unknown