Synthesis and Characterization of Novel Amino Acid-conjugated Poly(aspartic acid) Derivatives

Bulletin of the Korean chemical society

Seung Il Kim¹  Ji Heung Kim¹  Seok Kee Min¹ 

关键词: Nanoparticle;    Poly(aspartic acid);    Amphiphilic copolymer;    L-Lysine;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Novel poly(aspartic acid) derivatives conjugated with L-lysine moieties and their amphiphilic analogs were synthesized and characterized. The chemical structures of these polymers were confirmed using FT-IR and 1HNMR spectroscopy. The physicochemical properties of amphiphilic copolymers were characterized using an electrophonetic light scattering spectrophotometer (ELS) and transmission electron microscopy (TEM). These results indicated a stable nanoparticle formation within aqueous media. These polymers have potential applications in the pharmaceutical and cosmetic fields as delivery vehicles for bioactive molecules.

【 授权许可】

Unknown