期刊论文详细信息
Bulletin of the Korean chemical society | |
Synthesis of Calycotomine via Pictet-Spengler Type Reaction of N,O-Acetal TMS Ethers as N-Acyliminium Ion Equivalents | |
Heesoon Lee1  Mi-Sung Lee1  Young-Ger Suh1  Jin-Kyung In1  Jung-Eun Yang1  Jae-Kyung Jung1  Han-Young Kang1  Soo Jae Lee1  Jae-Hwan Kwak1  | |
关键词: Tetrahydroisoquinoline; Pictet-Spengler reaction; N; O-Acetal TMS ether; Alkaloid; | |
DOI : | |
学科分类:化学(综合) | |
来源: Korean Chemical Society | |
【 摘 要 】
An efficient Pictet-Spengler type reaction of N,O-acetal TMS ethers for the practical synthesis of 1-substituted tetrahydroquinolines, medicinally important alkaloids, has been accomplished. To demonstrate the versatility of this novel procedure, the total synthesis of calycotomine, a representative 1-hydroxymethyl substituted tetrahydroisoquinoline, is also described.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912010240619ZK.pdf | 576KB | download |