Nanoliter Reactor Arrays for Antibiotic Study

Bulletin of the Korean chemical society

Jin-Won Park¹ 

关键词: Nanoliter;    Reactor;    Arrays;    Vesicles;    Gramicidin;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

It is demonstrated in this study that the nanoliter reactor arrays with an inkjet printing, can be used for high throughput screen of antibiotic function. As a model antibiotic, gramicidin was used in this study. The gramicidin embedded lipid vesicles were immobilized on the surface in the nanoliter reactor structure with control of the volume in the nanoliter reactor. By dispensing acidic drops into the reactor, the gramicidin function was monitored. The technique developed in this research also has a great potential to be used for discovery of drugs.

【 授权许可】

Unknown