Stereoselective Crossed-Aldol Condensation of Hetarylmethyl Ketones with Aromatic Aldehydes in Water : Synthesis of (2E)-3-Aryl-1-hetarylprop-2-en-1-ones

Bulletin of the Korean chemical society

Salem A. Basaif¹  Mohamed A. Hassan¹  Tatiq R. Sobahi¹  Ali Kh. Khalil¹ 

关键词: Crossed-Aldol;    Hetarylpropenones;    Chalcones;    Synthesis in water;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Aldol condensation of 2-acetylthiophene, 2-acetylpyrrole and 2-acetylpyridine with different aromatic aldehydes were carried out in water in heterogeneous phases in the presence of cetyltrimethylammonium bromide as cationic surfactant at room temperature. All the reactions occur in a short time with excellent yields of steroselective hetarylpropanones in water as environmental friendly solvent.

【 授权许可】

Unknown