Zinc Mediated Barbier Type Allylation of Cyclic Imides and Subsequent Coupling Reactions with Carbon Nucleophiles

Bulletin of the Korean chemical society

Sung Hoon Kim¹  Eun Young Heo¹  Seok Won Kang¹  Jong Gab Jun¹ 

关键词: Allylation;    Cyclic imide;    Barbier;    N-Acyliminium ion;    Carbon nucleophiles;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Allylations of N-benzyl and N-methyl cyclic imides were accomplished successfully under mild Barbier type conditions using zinc metal, allyl bromide and catalytic amount of PbBr2. Subsequent coupling reactions with some carbon nucleophiles afforded 1,2- and 1,4-addition products in moderate to high yields.

【 授权许可】

Unknown