A Novel Route to New Bis(benzopyrano) Fused Dihydropyridines Using Dry Media

Bulletin of the Korean chemical society

Richa Mohan¹  Mazaahir Kidwai¹  Shweta Rastogi¹ 

关键词: Benzopyran;    Pyridine;    Solid support;    Microwave irradiation;    Ecofriendly;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A new and efficient synthesis of the novel bioactive bis(benzopyrano) fused dihydropyridines is described. The conventionally developed route is a two step multicomponent condensation reaction. This is latter modified by a one pot microwave (MW) assisted reaction using inorganic solid support via the arylidene derivative intermediate. With this environmentally benign approach, the reaction time is brought down from hours to minutes along with a yield enhancement. Furthermore, the role of different solid supports is studied and it is concluded that the acidic alumina is the best solid support for the present investigation.

【 授权许可】

Unknown