A Mild and Convenient Method for the Reduction of Carbonyl Compounds with NaBH4 in the Presence of Catalytic Amounts of MoCl5

Bulletin of the Korean chemical society

Behzad Zeynizadeh¹  Saiedeh Yahyaei¹ 

关键词: Reduction;    Sodium borohydride;    MoCl5;    Carbonyl compounds;    Alcohols;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

NaBH₄ with catalytic amounts of MoCl5 can readily reduce a variety of carbonyl compounds such as aldehydes, ketones, acyloins, �?-diketones and conjugated enones to their corresponding alcohols in good to excellent yields. Reduction reactions were performed under aprotic condition in CH3CN at room temperature or reflux. In addition, the chemoselective reduction of aldehydes over ketones was accomplished successfully with this reducing system.

【 授权许可】

Unknown