Photochemical Reaction of Nalidixic Acid in Methanol

Bulletin of the Korean chemical society

Ki-Min Bark¹  Hong-Yune Lee¹  Hyoung-Ryun Park¹  Ok-Hyun Park¹  Jung-Ja Seo¹ 

关键词: Photochemical reaction;    Nalidixic acid;    1-Ethyl-7-methyl-4-oxo-1;    4-hydro-1;    8-naphthyridine;    Formic acid;    Formaldehyde;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

The photochemical reactions of methanolic nalidixic acid (NAL) solution in the absence and in the presence of air have been investigated using 300 nm UV light. From the reactions, 1-ethyl-7-methyl-4-oxo-4-hydro-1,8-naphthyridine (EMDN), formic acid, and formaldehyde are produced. In the presence of air, hydrogen peroxide is also detected along with the products listed above. The presence of oxygen during the irradiation of methanolic NAL solution effects on the product yield. The initial quantum yields of the products and of the NAL decomposition are determined. Possible reaction pathways for the photochemical reaction are suggested on the basis of the products analysis.

【 授权许可】

Unknown