Tin-Free Three-Component Coupling Reaction of Aryl Halides, Norbornadiene (or Norbornene), and Alkynols Using a Palladium Catalyst

Bulletin of the Korean chemical society

Ikuyoshi Tomita¹  Takeshi Endo¹  Cheol-Kyu Choi¹  Jin-Who Hong¹ 

关键词: Aryl halides;    Norbornene;    Alkynols;    Palladium-catalyst;    Three-component reaction.;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

Good-to-excellent yields of 2,3-Disubstituted norbornenes (or norbornanes) were obtained using a Pd/Cu catalyzed three-component ternary coupling reaction of aryl halides, norbornadiene (or norbornene), and alkynols in toluene at 100 �? in the presence of 5.5 M NaOH as a base and benzyltriethylammonium chloride as a phase transfer catalyst. The results of experiments using various aromatic halides suggest that the ternary coupling reaction is promoted by bromide.

【 授权许可】

Unknown