Bulletin of materials science | |
Spectroscopic, thermal and biological studies of coordination compounds of sulfasalazine drug: Mn(II), Hg(II), Cr(III), ZrO(II), VO(II) and Y(III) transition metal complexes | |
M S Refat1  M G Abd El-Wahed2  S M El-Megharbel2  | |
[1] Department of Chemistry, Faculty of Science, Port Said, Suez Canal University, Port Said, Egypt$$Department of Chemistry, Faculty of Science, Port Said, Suez Canal University, Port Said, EgyptDepartment of Chemistry, Faculty of Science, Port Said, Suez Canal University, Port Said, Egypt$$;Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt$$Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, EgyptDepartment of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt$$ | |
关键词: Infrared spectra; electronic spectra; thermal analysis; sulfasalazine; antimicrobial activity.; | |
DOI : | |
学科分类:材料工程 | |
来源: Indian Academy of Sciences | |
【 摘 要 】
The complexations of sulfasalazine (H3Suz) with some of transition metals have been investigated. Three types of complexes, [Mn(HSuz)-2(H2O)4].2H2O, [M(HSuz)-2(H2O)2].ð‘¥H2O (M = Hg(II), ZrO(II) and VO(II), ð‘�? = 4, 8 and 6, respectively) and [M(HSuz)-2(Cl)(H2O)3].ð‘¥H2O (M = Cr(III) and Y(III), ð‘�? = 5 and 6, respectively) were obtained and characterized by physicochemical and spectroscopic methods. The IR spectra of the complexes suggest that the sulfasalazine behaves as a monoanionic bidentate ligand. The thermal decomposition of the complexes as well as thermodynamic parameters (ð›�? ð¸*}, ð›�? ð»*, ð›�? ð‘�??* and ð›�? ðº*) were estimated using Coatsâ€�?�Redfern and Horowitzâ€�?�Metzger equations. In vitro antimicrobial activities of the H3Suz and the complexes were tested.
【 授权许可】
Unknown
【 预 览 】
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