Development of calcium phosphate based bioceramics

Bulletin of materials science

A Ingle¹  A N Bhisey¹  B P Sharma⁴  S N Vaidya³  K R Munim²  Amit Sinha⁴ 

[1] Cancer Research Institute, Dr Ernest Borges Marg, Parel, Mumbai 400 012, India$$Cancer Research Institute, Dr Ernest Borges Marg, Parel, Mumbai 400 012, IndiaCancer Research Institute, Dr Ernest Borges Marg, Parel, Mumbai 400 012, India$$;Medical Division, Bhabha Atomic Research Centre, Mumbai 400 085, India$$Medical Division, Bhabha Atomic Research Centre, Mumbai 400 085, IndiaMedical Division, Bhabha Atomic Research Centre, Mumbai 400 085, India$$;High Pressure Physics Division, Bhabha Atomic Research Centre, Mumbai 400 085, India$$High Pressure Physics Division, Bhabha Atomic Research Centre, Mumbai 400 085, IndiaHigh Pressure Physics Division, Bhabha Atomic Research Centre, Mumbai 400 085, India$$;Powder Metallurgy Division, Bhabha Atomic Research Centre, Vashi Complex, Navi Mumbai 400 705, India$$Powder Metallurgy Division, Bhabha Atomic Research Centre, Vashi Complex, Navi Mumbai 400 705, IndiaPowder Metallurgy Division, Bhabha Atomic Research Centre, Vashi Complex, Navi Mumbai 400 705, India$$

关键词: Bioceramic;    calcium phosphate;    hydroxyapatite;    wollastonite;    biocompatibility.;   

DOI  :  

学科分类：材料工程

来源: Indian Academy of Sciences

【 摘 要 】

Two bioceramics (Ca�?�P�?�O glass and A�?�W glass ceramic) were produced using conventional methods of ceramic technology. X-ray powder diffraction patterns were used for identifying the phases and 3-point bend test was carried out for the determination of fracture strength of the bioceramics. Biocompatibility of both ceramics was evaluated using animal model experiments. Histological studies showed that A�?�W glass ceramic implanted in the tibia of rat formed an intimate contact with newly grown bone and provided enough strength to the bone to bear the animal weight. Implants made of Ca�?�P�?�O glass was almost fully resorbed and was replaced by new bone. The implants made of both the bioceramics were biocompatible and did not exhibit any kind of adverse effect to the surrounding tissues.

【 授权许可】

Unknown