High concordance of ALK rearrangement between primary tumor and paired metastatic lymph node in patients with lung adenocarcinoma

Journal of Thoracic Disease

Bo Su²  Wei Zhang⁴  Yan Huang⁴  Chunyan Wu⁴  Wei Wu⁴  Zhengwei Dong⁴  Gang Chen¹  Liping Zhang⁴  Shengxiang Ren³  Likun Hou⁴ 

[1] Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China;Central Lab, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, ChinaCentral Lab, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, ChinaCentral Lab, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China;Department of Medical Oncology,Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, ChinaDepartment of Medical Oncology,Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, ChinaDepartment of Medical Oncology,Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China;Department of Pathology,Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, ChinaDepartment of Pathology,Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, ChinaDepartment of Pathology,Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China

关键词: ALK rearrangement;    heterogeneity;    lung adenocarcinoma;    immunohistochemistry (IHC);    reverse transcriptase-polymerase chain reaction (RT-PCR);    fluorescence in situ hybridization (FISH);   

DOI  :  10.21037/jtd.2016.03.96

学科分类：呼吸医学

来源: Pioneer Bioscience Publishing Company

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