Enriching the Interventional Vision of Cancer with Fluorescence and Optoacoustic Imaging

Journal of Nuclear Medicine

Jürgen Glatz¹  Vasilis Ntziachristos¹  Maximilian Koch¹  P. Beatriz Garcia-Allende¹ 

[1] Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Munich, Germany Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Munich, Germany Institute for Biological and Medical Imaging, Technische Universität München and Helmholtz Zentrum München, Munich, Germany

关键词: fluorescence molecular imaging;    optoacoustic imaging;    photoacoustic imaging;    surgery;    endoscopy;    fluorescent agents;   

DOI  :  10.2967/jnumed.111.099796

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

Among several techniques considered for surgical and endoscopic imaging, novel optical methods are evolving as a promising approach for interventional guidance. Pilot clinical applications of fluorescence molecular imaging have demonstrated the benefits of using targeted fluorescent agents in cancer surgery. This premise can be extended broadly to interventional guidance through an increasing number of targeted agents and detection techniques. Beyond epi-illumination fluorescence imaging, optoacoustic (photoacoustic) methods are emerging to offer high-resolution cross-sectional optical imaging through several millimeters to centimeters of depth. We present an overview of key recent developments in optical interventional imaging and outline the potential for a paradigm shift in surgical and endoscopic visualization.

【 授权许可】

Unknown