A Portable γ-Camera for Intraoperative Detection of Sentinel Nodes in the Head and Neck Region

Journal of Nuclear Medicine

Michiel W.M. van den Brekel¹  W. Martin C. Klop¹  Alfons J.M. Balm¹  Lenka Vermeeren¹  Renato A. Valdés Olmos¹ 

关键词: sentinel lymph node biopsy;    gamma cameras;    head and neck neoplasms;   

DOI  :  10.2967/jnumed.109.071407

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

We introduced and evaluated a portable γ-camera for intraoperative visualization of sentinel nodes in the head and neck region. Methods: Planar lymphoscintigraphy and SPECT/CT were performed after peritumoral injection of 99mTc-nanocolloid in 25 patients (head and neck melanoma or oral cavity carcinoma). Sentinel nodes were localized intraoperatively with a portable γ-camera and a hand-held γ-probe. The portable γ-camera was used to determine the distribution of remaining radioactivity after excision of the sentinel nodes. Results: The portable γ-camera visualized all 70 preoperatively identified sentinel nodes. Sentinel nodes at difficult sites could be localized more efficiently, and in 6 patients, 9 additional nodes (1 tumor-positive) were identified with the portable γ-camera after excision. Conclusion: Intraoperative identification of sentinel nodes in the head and neck region with a portable γ-camera is feasible and might lead to detection of more sentinel nodes.

【 授权许可】

Unknown