Influence of Bowel Preparation Before 18F-FDG PET/CT on Physiologic 18F-FDG Activity in the Intestine

Journal of Nuclear Medicine

Daniel T. Schmid¹  Patrick Veit-Haibach¹  Niklaus G. Schaefer¹  Alois Tschopp¹  Thomas F. Hany¹  Jan D. Soyka¹  Klaus Strobel¹ 

关键词: gastroenterology;    oncology;    PET/CT;    FDG uptake;    bowel preparation;    intestinal;    physiologic;   

DOI  :  10.2967/jnumed.109.071001

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

Our objective was to investigate the use of bowel preparation before 18F-FDG PET/CT to reduce intestinal 18F-FDG uptake. Methods: Sixty-five patients with abdominal neoplasias were assigned either to a bowel-preparation group (n = 26) or to a native group (n = 39). 18F-FDG activity was measured in the small intestine and the colon. Results: In the 26 patients with bowel preparation, average maximal standardized uptake value (SUVmax) was 3.5 in the small intestine and 4.4 in the colon. In the 39 patients without bowel preparation, average SUVmax was 2.6 in the small intestine and 2.7 in the colon. 18F-FDG activity impaired diagnosis in 6 patients (23%) in the bowel-preparation group and 11 patients (28%) in the native group (P = 0.5). SUVmax in the colon was significantly higher in the bowel-preparation group (P = 0.002), but SUVmax in the small intestine did not significantly differ between the 2 groups (P = 0.088). Conclusion: Bowel preparation increases 18F-FDG activity in the large intestine and is therefore not useful before PET/CT.

【 授权许可】

Unknown