Diagnosis of Cirrhotic Portal Hypertension and Compensatory Circulation Using Transsplenic Portal Scintigraphy with 99mTc-Phytate

Journal of Nuclear Medicine

Changzheng Ren¹  Fuyong Yang¹  Hua Li¹  Li Gao¹  Jiankui Han¹  Youan Zhao¹ 

关键词: cirrhosis;    portal hypertension;    portal scintigraphy;    compensatory circulation;    portosystemic shunt;   

DOI  :  10.2967/jnumed.109.067983

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

Our objective was to investigate the diagnostic value and clinical significance of transsplenic portal scintigraphy in cirrhotic portal hypertension and compensatory circulation. Methods: Transsplenic portal scintigraphy, ultrasound, and gastroscopy were performed on 50 patients with cirrhotic portal hypertension and on 10 controls. According to the Child–Pugh classification, 15 patients with cirrhosis were Child A, 19 were Child B, and 16 were Child C. Results: In the control group, the splenoportal vein was shaped like the letter S, and the portosystemic shunt index was 0.19 ± 0.07. Portal hypertension portosystemic shunts were of 3 types: intrahepatic (13 patients; index, 0.52 ± 0.19), compensatory (31 patients; index, 0.64 ± 0.28); and completely extrahepatic (6 patients; index, 0.91 ± 0.03). Collateral vessels were uphill, downhill, or complex. The portosystemic shunt index increased as cirrhosis and esophageal varices increased. There was statistical significance among groups (P < 0.05 or < 0.01). Conclusion: Transsplenic portal scintigraphy was sensitive for detecting the number and location of shunts and will allow for improved surgical planning.

【 授权许可】

Unknown