Radioisotopic Imaging of Neuroinflammation

Journal of Nuclear Medicine

Alexandra Winkeler¹  Raphaël Boisgard¹  Bertrand Tavitian¹  Abraham Martin¹ 

关键词: neuroinflammation;    microglia;    blood-brain barrier;    cell tracking;    positron emission tomography;    peripheral benzodiazepine receptor;   

DOI  :  10.2967/jnumed.109.065680

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

Inflammatory responses are closely associated with many neurologic disorders and influence their outcome. In vivo imaging can document events accompanying neuroinflammation, such as changes in blood flow, vascular permeability, tightness of the blood-to-brain barrier, local metabolic activity, and expression of specific molecular targets. Here, we briefly review current methods for imaging neuroinflammation, with special emphasis on nuclear imaging techniques.

【 授权许可】

Unknown