Optical Imaging: Current Applications and Future Directions

Journal of Nuclear Medicine

Kathryn E. Luker¹  Gary D. Luker¹ 

[1] University of Michigan Ann Arbor, Michigan University of Michigan Ann Arbor, Michigan University of Michigan Ann Arbor, Michigan

关键词: bioluminescence imaging;    fluorescence imaging;    optical imaging probes;   

DOI  :  10.2967/jnumed.107.045799

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

Optical techniques, such as bioluminescence and fluorescence, are emerging as powerful new modalities for molecular imaging in disease and therapy. Combining innovative molecular biology and chemistry, researchers have developed optical methods for imaging a variety of cellular and molecular processes in vivo, including protein interactions, protein degradation, and protease activity. Whereas optical imaging has been used primarily for research in small-animal models, there are several areas in which optical molecular imaging will translate to clinical medicine. In this review, we summarize recent advances in optical techniques for molecular imaging and the potential impact for clinical medicine.

【 授权许可】

Unknown