Online monitoring of ethanol concentration using a responsive microfluidic membrane device

Analytical Methods

Li-Ping Zhang¹  Xiao-Jie Ju²  Xiao-Yi Zou¹  Liang-Yin Chu³  Rui Xie¹  Feng Luo¹  Wei Wang¹  Zhuang Liu¹ 

[1] School of Chemical Engineering, Sichuan University,Chengdu,ChinaSchool of Chemical Engineering, Sichuan University,Chengdu,ChinaSchool of Chemical Engineering, Sichuan University,Chengdu,China;School of Chemical Engineering, Sichuan University,Chengdu,ChinaState Key Laboratory of Polymer Materials Engineering, Sichuan University,Chengdu,ChinaSchool of Chemical Engineering, Sichuan University,Chengdu,ChinaSchool of Chemical Engineering, Sichuan University,Chengdu,ChinaState Key Laboratory of Polymer Materials Engineering, Sichuan University,Chengdu,ChinaState Key Laboratory of Polymer Materials Engineering, Sichuan University,Chengdu,ChinaSchool of Chemical Engineering, Sichuan University,Chengdu,ChinaState Key Laboratory of Polymer Materials Engineering, Sichuan University,Chengdu,China;School of Chemical Engineering, Sichuan University,Chengdu,ChinaState Key Laboratory of Polymer Materials Engineering, Sichuan University,Chengdu,ChinaJiangsu National Synergetic Innovation Center for Advanced Materials (SICAM),Nanjing,ChinaSchool of Chemical Engineering, Sichuan University,Chengdu,ChinaSchool of Chemical Engineering, Sichuan University,Chengdu,ChinaState Key Laboratory of Polymer Materials Engineering, Sichuan University,Chengdu,ChinaJiangsu National Synergetic Innovation Center for Advanced Materials (SICAM),Nanjing,ChinaState Key Laboratory of Polymer Materials Engineering, Sichuan University,Chengdu,ChinaSchool of Chemical Engineering, Sichuan University,Chengdu,ChinaState Key Laboratory of Polymer Materials Engineering, Sichuan University,Chengdu,ChinaJiangsu National Synergetic Innovation Center for Advanced Materials (SICAM),Nanjing,ChinaJiangsu National Synergetic Innovation Center for Advanced Materials (SICAM),Nanjing,ChinaSchool of Chemical Engineering, Sichuan University,Chengdu,ChinaState Key Laboratory of Polymer Materials Engineering, Sichuan University,Chengdu,ChinaJiangsu National Synergetic Innovation Center for Advanced Materials (SICAM),Nanjing,China

DOI  :  10.1039/C6AY00432F

学科分类：分析化学

来源: Royal Society of Chemistry

【 摘 要 】

A novel method for online monitoring of ethanol concentration has been proposed by successfully developing an ethanol-responsive microfluidic membrane device. The microfluidic membrane device is fabricated by bonding two patterned polydimethylsiloxane (PDMS) modules with a sandwiched ethanol-responsive membrane via a “stamp-like” method. The PDMS modules are prepared by soft lithography and the ethanol-responsive membrane is prepared by blending poly(N-isopropylacrylamide) nanogels into the membrane-forming solution via a vapor-induced phase separation process. The developed microfluidic membrane device shows excellent ethanol-responsive characteristics, rapid responsive rate, and good repeatability and stability. With the microfluidic membrane device, a significant difference in fluxes of ethanol solutions with different concentrations can be directly observed. At certain temperatures, the microfluidic membrane device shows critical responsive ethanol concentrations around 10 vol%, e.g., 13.0 vol% at 25 °C and 7.8 vol% at 30 °C. For real fermentation broths, the microfluidic membrane device still shows excellent response and detection performances, which demonstrates that the microfluidic membrane device is highly promising to be applied to monitor the ethanol concentration in fermentation processes.

【 授权许可】

Unknown