Dual-aptamer-based sensitive and selective detection of prion protein through the fluorescence resonance energy transfer between quantum dots and graphene oxide

Analytical Methods

Shu Jun Zhen³  Jian Wang¹  Hong Lin Zhuang³  Cheng Zhi Huang² 

[1] College of Pharmaceutical Sciences, Southwest University,Chongqing 400715,ChinaCollege of Pharmaceutical Sciences, Southwest University,Chongqing 400715,ChinaCollege of Pharmaceutical Sciences, Southwest University,Chongqing 400715,China;Education Ministry Key Laboratory on Luminescence and Real-Time Analysis, College of Chemistry and Chemical Engineering, Southwest University,Chongqing 400715,ChinaCollege of Pharmaceutical Sciences, Southwest University,Chongqing 400715,ChinaEducation Ministry Key Laboratory on Luminescence and Real-Time Analysis, College of Chemistry and Chemical Engineering, Southwest University,Chongqing 400715,ChinaEducation Ministry Key Laboratory on Luminescence and Real-Time Analysis, College of Chemistry and Chemical Engineering, Southwest University,Chongqing 400715,ChinaCollege of Pharmaceutical Sciences, Southwest University,Chongqing 400715,ChinaCollege of Pharmaceutical Sciences, Southwest University,Chongqing 400715,ChinaEducation Ministry Key Laboratory on Luminescence and Real-Time Analysis, College of Chemistry and Chemical Engineering, Southwest University,Chongqing 400715,ChinaCollege of Pharmaceutical Sciences, Southwest University,Chongqing 400715,China;Education Ministry Key Laboratory on Luminescence and Real-Time Analysis, College of Chemistry and Chemical Engineering, Southwest University,Chongqing 400715,ChinaEducation Ministry Key Laboratory on Luminescence and Real-Time Analysis, College of Chemistry and Chemical Engineering, Southwest University,Chongqing 400715,ChinaEducation Ministry Key Laboratory on Luminescence and Real-Time Analysis, College of Chemistry and Chemical Engineering, Southwest University,Chongqing 400715,China

DOI  :  10.1039/C3AY41335G

学科分类：分析化学

来源: Royal Society of Chemistry

【 摘 要 】

We developed a new dual-aptamer based strategy to detect cellular prion protein through the fluorescence resonance energy transfer between quantum dots and graphene oxide, in which the distance between the energy donor and the acceptor ranges from 14 to 27 nm.

【 授权许可】

Unknown