期刊论文详细信息
Journal of Nuclear Medicine Technology
Evaluation of Patients with Head and Neck Cancer by Means of 99mTc-Glucarate
Lucía Delgado1  Martín Lafferranderie1  Omar Alonso1  Javier Noble1  Juan P. Gambini1  Ricardo D'Albora1  Margarita Nuñez1  Eduardo Corchs1  Eduardo Savio1  Pablo Cabral1 
关键词: head and neck tumors;    99mTc-glucarate;    SPECT/CT software fusion;   
DOI  :  10.2967/jnmt.109.062927
学科分类:医学(综合)
来源: Society of Nuclear Medicine
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【 摘 要 】

Preliminary findings have suggested that 99mTc-glucarate has tumor-seeking properties. The purpose of this study was to explore the potential of this tracer to evaluate malignant head and neck tumors by means of SPECT/CT software fusion imaging. Methods: Eleven male patients with advanced head and neck carcinoma were included in the study: 9 with locally advanced disease and 2 with clinical suspicion of local relapse. Scanning started 3–6 h after the injection of 1,110 MBq of 99mTc-glucarate. Planar and SPECT images of the head, neck, and thorax were acquired. Three-dimensional images were also coregistered with CT. Results: We found 99mTc-glucarate uptake in all suspected lesions. SPECT/CT fusion imaging was helpful in all cases for topographically localizing the tracer foci. Conclusion: 99mTc-glucarate can be considered a potential tracer for the evaluation of patients with head and neck tumors.

【 授权许可】

Unknown   

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