Preoperative Evaluation of Sentinel Lymph Node Status in Melanoma by Means of 99mTc-MIBI and Lymphoscintigraphy: A Case Report

Journal of Nuclear Medicine Technology

Omar Alonso¹  José Espasandin¹  Graciela Lago¹  Miguel Martínez¹ 

[1] Nuclear Medicine Center and Department of Dermatology, Clinical Hospital of the University of Uruguay, Montevideo; and National Institute of Oncology, Montevideo, Uruguay Nuclear Medicine Center and Department of Dermatology, Clinical Hospital of the University of Uruguay, Montevideo; and National Institute of Oncology, Montevideo, Uruguay Nuclear Medicine Center and Department of Dermatology, Clinical Hospital of the University of Uruguay, Montevideo; and National Institute of Oncology, Montevideo, Uruguay

关键词: lymphoscintigraphy;    melanoma;    sentinel lymph nodes;    ^99mTc-MIBI;   

DOI  :  

学科分类：医学（综合）

来源: Society of Nuclear Medicine

【 摘 要 】

Previous reports have shown that 99mTc-sestamibi (MIBI) could detect clinically occult metastatic melanoma lesions. This article reports on a patient with invasive melanoma of the right heel in whom the sentinel node status was preoperatively evaluated with this tracer. Although regional lymph nodes were clinically negative, 99mTc-MIBI scintigraphy showed focal increased tracer uptake in the right groin that corresponded to the location of 2 sentinel nodes visualized by lymphoscintigraphy with 99mTc-colloidal rhenium sulfide performed the same day. A γ-probe was used intraoperatively to guide the excision of the sentinel nodes that were further classified as metastatic by histopathology. This double-technique approach is technically feasible and has the potential of selecting a group of patients who might benefit from a selective complete lymphadenectomy.

【 授权许可】

Unknown