期刊论文详细信息
PLOS Pathogens
Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology
David A. Fidock1  Matthew R. Hassett1  Lise Musset1  Nina F. Gnädig1  Philipp P. Henrich1  Paul S. Callaghan1  Stanislaw J. Gabryszewski1  Jill M. Combrinck1  Paul D. Roepe1  Andrew H. Lee1  Ian A. Lewis1  Satish K. Dhingra1  Manuel Llinás1  Timothy J. Egan1  Amila Siriwardana1 
关键词: Heme;    Antimicrobial resistance;    Metabolites;    Plasmodium;    Drug metabolism;    Antimalarials;    Haplotypes;    Chloroquine;   
DOI  :  10.1371/journal.ppat.1005976
学科分类:生物科学(综合)
来源: Public Library of Science
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