TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection

PLOS Pathogens

Gabriela M. Webb¹  Mario Ostrowski¹  Brooks I. Mitchell¹  Kiera L. Clayton¹  Alan J. Korman¹  Glen M. Chew¹  Katherine B. Hammond¹  Benjamin J. Burwitz¹  Jason S. Reed¹  Steven G. Deeks¹  Teri Liegler¹  Naoto Ishii¹  Tsuyoshi Fujita¹  Frederick M. Hecht¹  Mohamed Abdel-Mohsen¹  Cecilia M. Shikuma¹  Jonah B. Sacha¹  Lishomwa C. Ndhlovu¹  Scott G. Hansen¹  Helen L. Wu¹  Mark Maurer¹ 

关键词: T cells;    Cytotoxic T cells;    HIV-1;    Flow cytometry;    HIV;    Cytokines;    HIV infections;    Macaque;   

DOI  :  10.1371/journal.ppat.1005349

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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