The HIV-1 Envelope Transmembrane Domain Binds TLR2 through a Distinct Dimerization Motif and Inhibits TLR2-Mediated Responses

PLOS Pathogens

Etai Rotem¹  Mohammad Ali¹  Andrea Gramatica¹  Anthony H. Futerman¹  Roland Schwarzter¹  Yechiel Shai¹  Eliran Moshe Reuven¹ 

关键词: Toll-like receptors;    HIV-1;    Macrophages;    Immune receptor signaling;    Mouse models;    Secretion;    Cytokines;    Spleen;   

DOI  :  10.1371/journal.ppat.1004248

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

Unknown