Forward Genetic Screening Identifies a Small Molecule That Blocks Toxoplasma gondii Growth by Inhibiting Both Host- and Parasite-Encoded Kinases

PLOS Pathogens

Graham B. Wiley¹  Elena Suvorova¹  Marc Jan Gubbels¹  Kevin M. Brown¹  Patrick M. Gaffney¹  Aaron McLain¹  Michael White¹  Andrew Farrell¹  Ashley Dittmar¹  Ira J. Blader¹  Gabor Marth¹ 

关键词: Parasite replication;    Parasitic diseases;    Toxoplasma;    Host-pathogen interactions;    Kinase inhibitors;    Tachyzoites;    Host cells;    Parasitic cell cycles;   

DOI  :  10.1371/journal.ppat.1004180

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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