H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis

PLOS Pathogens

Albert D. M. E. Osterhaus¹  Junfeng Liu¹  Charles A. B. Boucher¹  Lesley F. Haire¹  Philip A. Walker¹  Erhard van der Vries¹  Steve R. Martin¹  John J. Skehel¹  Alan J. Hay¹  Patrick J. Collins¹  Steve J. Gamblin¹  Martin Schutten¹  Xiaoli Xiong¹  Sebastien G. Vachieri¹ 

关键词: Antimicrobial resistance;    Crystal structure;    Influenza viruses;    Hydrogen bonding;    Neuraminidase inhibitors;    Influenza;    Arginine;    H1N1;   

DOI  :  10.1371/journal.ppat.1002914

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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