PK-sensitive PrPSc Is Infectious and Shares Basic Structural Features with PK-resistant PrPSc

PLOS Pathogens

Ester Vázquez-Fernández¹  Adriana Ramos¹  Christina J. Sigurdson¹  Miguel A. Pastrana¹  Elizabeth M. Antaki¹  Irina Dynin¹  J. Mark Carter¹  Bruce C. Onisko¹  Melissa L. Erickson¹  Christopher J. Silva¹  Gustavo Sajnani¹  Jesús R. Requena¹ 

关键词: Hamsters;    Animal prion diseases;    Sonication;    Chlorides;    Matrix-assisted laser desorption ionization time-of-flight mass spectrometry;    Immunohistochemistry techniques;    Proteases;    Proteolysis;   

DOI  :  10.1371/journal.ppat.1002547

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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