Hsp90 Inhibitors Are Efficacious against Kaposi Sarcoma by Enhancing the Degradation of the Essential Viral Gene LANA, of the Viral Co-Receptor EphA2 as well as Other Client Proteins

PLOS Pathogens

Blossom Damania¹  Wuguo Chen¹  Dirk P. Dittmer¹  Kwun Wah Wen¹  Sang-Hoon Sin¹ 

关键词: Immunoprecipitation;    Heat shock response;    Kaposi sarcoma;    Kaposi's sarcoma-associated herpesvirus;    Apoptosis;    DNA-binding proteins;    HeLa cells;    Cancer treatment;   

DOI  :  10.1371/journal.ppat.1003048

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

Unknown