Envelope Deglycosylation Enhances Antigenicity of HIV-1 gp41 Epitopes for Both Broad Neutralizing Antibodies and Their Unmutated Ancestor Antibodies

PLOS Pathogens

Xiaozhi Lu¹  Georgia D. Tomaras¹  Laura L. Sutherland¹  Cindy Bowman¹  Heather Desaire¹  Hua-Xin Liao¹  Norman L. Letvin¹  Barton F. Haynes¹  Sampa Santra¹  Eden P. Go¹  Thomas B. Kepler¹  Richard M. Scearce¹  S. Munir Alam¹  Ben-Jiang Ma¹ 

关键词: HIV-1;    Antibodies;    Enzyme-linked immunoassays;    Antigens;    Binding analysis;    Glycosylation;    B cells;    B cell receptors;   

DOI  :  10.1371/journal.ppat.1002200

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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