Small Molecule Inhibitors of Staphylococcus aureus RnpA Alter Cellular mRNA Turnover, Exhibit Antimicrobial Activity, and Attenuate Pathogenesis

PLOS Pathogens

Christelle M. Roux¹  Khalid Sayood¹  Sonja Daily¹  Jerry W. Simecka¹  Kelsi L. Anderson¹  Patrick D. Olson¹  Paul M. Dunman¹  Tami L. Lewis¹  Phung Nguyen¹  John M. Morrison¹  Mark S. Smeltzer¹  William J. Weiss¹  Eric P. Skaar¹  Karen E. Beenken¹  Lisa J. Kuechenmeister¹  Mark Pulse¹  Oluwatoyin A. Asojo¹  Michelle L. Reniere¹ 

关键词: Staphylococcus aureus;    Ribonucleases;    Messenger RNA;    Methicillin-resistant Staphylococcus aureus;    Antimicrobials;    Virulence factors;    Antisense RNA;    Vancomycin;   

DOI  :  10.1371/journal.ppat.1001287

学科分类：生物科学（综合）

来源: Public Library of Science

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