Two Novel Point Mutations in Clinical Staphylococcus aureus Reduce Linezolid Susceptibility and Switch on the Stringent Response to Promote Persistent Infection

PLOS Pathogens

Torsten Seemann¹  Benjamin P. Howden¹  Elizabeth L. Hartland¹  Hayley J. Newton¹  Timothy P. Stinear¹  Hyun-Woo Rhee¹  Paul F. Harrison¹  Jong-In Hong¹  John K. Davies¹  Natasha E. Holmes¹  Kyra Chua¹  Wei Gao¹ 

关键词: Staphylococcus aureus;    Gene regulation;    Methicillin-resistant Staphylococcus aureus;    Vancomycin;    Enzymes;    Gene expression;    Insertion mutation;    Antimicrobial resistance;   

DOI  :  10.1371/journal.ppat.1000944

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

Unknown