Impaired Innate Immunity in Tlr4−/− Mice but Preserved CD8+ T Cell Responses against Trypanosoma cruzi in Tlr4-, Tlr2-, Tlr9- or Myd88-Deficient Mice

PLOS Pathogens

Fabieni S. Neves¹  Maria Bellio¹  Raquel N. da Silva¹  Marcelo F. Santiago¹  Ana-Carolina Oliveira¹  Gisele S. Cavalcanti¹  Alberto Nóbrega¹  Marise P. Nunes¹  Silvia Boscardin¹  Weberton Klezewsky¹  Fanny Tzelepis¹  Bruna C. de Alencar¹  Maurício M. Rodrigues¹ 

关键词: Trypanosoma cruzi;    Parasitic diseases;    Cytotoxic T cells;    Toll-like receptors;    T cells;    Macrophages;    Trypomastigotes;    Immune response;   

DOI  :  10.1371/journal.ppat.1000870

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

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