Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41

PLOS Pathogens

Carole A. Bewley¹  Elena Gustchina¹  John M. Louis¹  Christian Frisch¹  Alexander Wlodawer¹  D. Eric Anderson¹  Mi Li¹  Alla Gustchina¹  G. Marius Clore¹  John Lloyd¹ 

关键词: Crystal structure;    HIV-1;    Hydrogen bonding;    Carbon;    Antibodies;    Isothermal titration calorimetry;    Membrane fusion;    Tryptophan;   

DOI  :  10.1371/journal.ppat.1001182

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

Unknown