Long-term follow-up of a patient since the acute phase of Chagas disease (South American trypanosomiasis): further treatment and cure of the infection

Revista da Sociedade Brasileira de Medicina Tropical

Dias, João Carlos Pinto¹  Dias, Emmanuel¹  Fundação Oswaldo Cruz, Belo Horizonte, Brazil¹  Nóbrega, Genard Carneiro da Cunha¹  Fundação Oswaldo Cruz, Rio de Janeiro, Brazil¹ 

关键词:  Chagas disease;    Specific treatment;    Evolution;    Cure;   

DOI  :  10.1590/0037-8682-0073-2015

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

A woman had been followed since 1957 for acute phase Chagas disease. Parasitological and serological tests were positive, and treatment included benznidazole in 1974. Following treatment, parasitological test results were negative and conventional serology remained positive until 1994, with subsequent discordant results (1995-1997). The results became consistently negative since 1999. She had an indeterminate chronic form until 1974. Only two minor and transitory nonspecific alterations on electrocardiogram were noted, with the last nine records normal until June 2014. This case confirms the possibility of curing chronic disease and suggests the benefit of specific treatments for preventing long-term morbidity.Keywords: Chagas disease; Specific treatment; Evolution; Cure

【 授权许可】

Unknown