Chagas disease in the State of Amazonas: history, epidemiological evolution, risks of endemicity and future perspectives

Revista da Sociedade Brasileira de Medicina Tropical

Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil¹  Santana, Rosa Amélia Gonçalves¹  Ferreira, João Marcos Bemfica Barbosa¹  Guerra, Jorge Augusto de Oliveira¹  Magalhães, Laylah Kelre Costa¹  Monteiro, Wuelton Marcelo¹  Silveira, Henrique¹  Universidade do Estado do Amazonas, Manaus, Brazil¹  Barbosa, Maria das Graças Vale¹  Mota, Daniel Testa¹  Fundação de Vigilância em Saúde, Manaus, Brazil¹  Universidade Nova de Lisboa, Lisboa, Portugal¹  Hospital Francisca Mendes, Manaus, Brazil¹  Magalhães, Laise Kelma Costa¹  Arcanjo, Ana Ruth Lima¹  Fé, Nelson Ferreira¹  Universidade Nilton Lins, Manaus, Brazil¹ 

关键词: Chagas' disease;    Brazilian Amazon;    State of Amazonas;    Trypanosoma cruzi;   

DOI  :  10.1590/0037-8682-0258-2013

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Chagas disease (CD) is a parasitic infection that originated in the Americas and is caused by Trypanosoma cruzi. In the last few years, the disease has spread to countries in North America, Asia and Europe due to the migration of Latin Americans. In the Brazilian Amazon, CD has an endemic transmission, especially in the Rio Negro region, where an occupational hazard was described for piaçaveiros (piassaba gatherers). In the State of Amazonas, the first chagasic infection was reported in 1977, and the first acute CD case was recorded in 1980. After initiatives to integrate acute CD diagnostics with the malaria laboratories network, reports of acute CD cases have increased. Most of these cases are associated with oral transmission by the consumption of contaminated food. Chronic cases have also been diagnosed, mostly in the indeterminate form. These cases were detected by serological surveys in cardiologic outpatient clinics and during blood donor screening. Considering that the control mechanisms adopted in Brazil's classic transmission areas are not fully applicable in the Amazon, it is important to understand the disease behavior in this region, both in the acute and chronic cases. Therefore, the pursuit of control measures for the Amazon region should be a priority given that CD represents a challenge to preserving the way of life of the Amazon's inhabitants.Key words: Chagas' disease; Brazilian Amazon; State of Amazonas; Trypanosoma cruzi

【 授权许可】

Unknown