Uneventful benznidazole treatment of acute Chagas disease during pregnancy: a case report

Revista da Sociedade Brasileira de Medicina Tropical

Barbosa, Fernanda Gama¹  Andrade Junior, Heitor Franco de¹  Hospital de Doenças Topicais de Araguaina, Araguaina, Brasil¹  Nascimento, Nanci¹  Castro, Luis Fernando D'Albuquerque e¹  Corrêa, Valeria Rita¹  Instituto Tocantinense Presidente Antonio Carlos, Araguaina, Brasil¹  Instituto de Pesquisas Energéticas e Nucleares, São Paulo, Brazil¹  Melo Junior, Claudimar Américo de¹  Instituto de Doenças do Tórax, Araguaina, Brasil¹  Universidade de São Paulo, São Paulo, Brazil¹ 

关键词: Acute Chagas disease;    Benznidazole;    Pregnancy;   

DOI  :  10.1590/0037-8682-0250-2013

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

This report describes the case of a patient with acute Chagas disease in Tocantins, Brazil, who was unaware of her pregnancy during benznidazole treatment. She presented with impaired cardiac function during the acute phase (pericarditis and incomplete right bundle-branch block) that resolved favorably after benznidazole therapy. Serological results also became negative, as determined by hemagglutination assays, enzyme-linked immunosorbent assays, and immunofluorescence assays. The child was born without sequelae and showed no evidence of congenital Trypanosoma cruzi infection at birth or 24 days later.Key words: Acute Chagas disease; Benznidazole; Pregnancy

【 授权许可】

Unknown