Fluconazole and amphotericin-B resistance are associated with increased catalase and superoxide dismutase activity in Candida albicans and Candida dubliniensis

Revista da Sociedade Brasileira de Medicina Tropical

Morsch, Vera Maria¹  Universidade Federal de Santa Maria, Santa Maria, BRAZIL¹  Giacomelli, Sandro Rogerio¹  Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil¹  Alves, Sydney Hartz¹  Schetinger, Maria Rosa Chitolina¹  Universidade Regional do Alto Uruguai e das Missoes, Frederico Westphalen, Brasil¹  Altenhofen, Delsi¹  Linares, Carlos Eduardo Blanco¹ 

关键词: Catalase;    Superoxide dismutase;    Candida albicans;    Candida dubliniensis;   

DOI  :  10.1590/0037-8682-0190-2013

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

IntroductionCandida dubliniensis, a new species of Candida thathas been recovered from several sites in healthy people, has been associated with recurrent episodesof oral candidiasis in AIDS and HIV-positive patients. This species is closely related to C.albicans. The enzymatic activity of C. dubliniensis in response tooxidative stress is of interest for the development of drugs to combat C.dubliniensis.

【 授权许可】

Unknown