Mother-to-child transmission of HIV infection in Manaus, State of Amazonas, Brazil

Revista da Sociedade Brasileira de Medicina Tropical

Miranda, Angélica Espinosa¹  Talhari, Sinésio¹  Universidade Estadual do Amazonas, Manaus¹  Secretaria Municipal de Saúde do Rio de Janeiro, Rio de Janeiro¹  Ferreira, Luiz Carlos de Lima¹  Saraceni, Valeria¹  Universidade Federal do Espírito Santo, Vitória¹  Soeiro, Claudia Marques de Oliveira¹  Lucena, Noaldo Oliveira de¹ 

关键词: Vertical transmission;    HIV;    AIDS;    Pregnancy;    Prophylaxis;   

DOI  :  10.1590/S0037-86822011000500001

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

INTRODUCTION: Reduction in the vertical transmission of HIV is possible when prophylactic measures are implemented. Our objective was to determine demographic characteristics of HIV-infected pregnant women and the rate of mother-to-child transmission of HIV in Manaus, Amazonas, Brazil.METHODS: A descriptive study was conducted using notification, and investigating data from the Notifiable Diseases Data System in the Brazilian State of Amazonas, between 2007 and 2009.RESULTS: During the study period, notification was received of 509 HIV-positive pregnant women. The vertical transmission was 9.9% (95% CI: 7.2-12.6%). The mean age of women was 27 years (SD: 5.7), and the majority (54.8%) had not completed elementary school (eighth grade). Diagnosis of HIV seropositivity was made prior to pregnancy in 115 (22.6%) women, during prenatal care in 302 (59.3%), during delivery in 70 (13.8%), and following delivery in 22 (4.3%). Four hundred four of these women (79.4%) had had prenatal care, with 79.4% of patients receiving antiretroviral during pregnancy and 61.9% of the newborn infants receiving prophylaxis. In the final multivariate logistic regression model, living in urban area [OR = 0.7 (95% CI: 0.35-0.89)] and having had prenatal care [OR = 0.1 (95% CI: 0.04-0.24)] remained as protective factors against vertical HIV transmission in this population.CONCLUSIONS: The relevance of adequate compliance with the measures already established as being effective in guaranteeing a reduction in HIV transmission within the maternal and infant population should be emphasized.

【 授权许可】

Unknown