Community prevalence of methicillin and vancomycin resistant Staphylococcus aureus in and around Bangalore, southern India

Revista da Sociedade Brasileira de Medicina Tropical

Universidade de Tecnologia, Africa do Sul¹  Neogi, Ujjwal¹  Chalannavar, Raju¹  Naidu, Kesava¹  Gupta, Soham¹  Faculdade de Gestão Administrativa, Bangalore, India¹  Subhaschandra, Gaddad¹  Agarwal, Deepali¹  Faculdade de Medicina St. John's, Bangalore, India¹  Faculdade Seema, India¹  Goud, Rajendra¹  Universidade Gulbarga, Gulbarga, India¹ 

关键词: Staphylococcus aureus;    Methicillin resistance;    Vancomycin resistance;    Healthy population;    Colonization;   

DOI  :  10.1590/S0037-86822011005000035

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

INTRODUCTION: Staphylococcus aureus is a known colonizer in humans and has been implicated in community acquired soft tissue infections. However emergence of methicillin resistant S. aureus (MRSA) has aroused great concern worldwide. This study aimed to determine the prevalence of MRSA in the community of Bangalore, southern India.METHODS: Swabs were collected from anterior nares, forearm, dorsum and palm of the hands of 1,000 healthy individuals residing in and around Bangalore, belonging to different socioeconomic strata and age groups.RESULTS: Analysis verified that 22.5% and 16.6% of the individuals presented Staphylococcus aureus and MRSA, respectively, at any of the three sites. Vancomycin resistance was observed in 1.4% of the S. aureus isolates, which was confirmed by detection of the vanA gene. It was interesting to note that 58.8% of the children in the age group 1-5 years-old presented MRSA, the highest percentage compared to other age groups of < 1 (44.4%) year-old, 5-20 (21.7%) years-old, > 40 (11%) years-old and 20-40 (9.9%) years-old. Among the population of various socioeconomic strata, maximum MRSA colonization was observed among doctors (22.2%), followed by upper economic class (18.8%), lower economic class (17.7%), apparently healthy hospital in-patients (16.5%), nurses (16%) and middle economic class (12.5%). Most of the MRSA isolates were capsular polysaccharide antigen type 8 (57.1%).CONCLUSIONS: There is a need for continuous surveillance and monitoring of the presence of MRSA in the community and a clearer understanding of the dynamics of the spread of MRSA will assist in controlling its dissemination.

【 授权许可】

Unknown