Sustained virological response in patients with coinfection by hepatitis C virus genotypes 1 and 2, after just nine weeks of antiviral therapy: case report

Revista da Sociedade Brasileira de Medicina Tropical

Levi, José Eduardo¹  Talhari, Sinésio¹  Torres, Kátia Luz¹  Instituto de Medicina Tropical de São Paulo, São Paulo¹  Universidade Federal do Amazonas, Manaus¹  Malheiro, Adriana¹  Araújo, Ana Ruth¹  Fundação de Medicina Tropical do Amazonas, Manaus¹  Almeida, Carlos Mauríco de¹  Fundação de Hematologia e Hemoterapia do Amazonas, Manaus¹  Victória, Marilu¹  Victória, Flamir¹  Maia, Laura Patrícia Viana¹  Tarragô, Andréa Monteiro¹  Lima, Tatiane Amábili de¹ 

关键词: Hepatite C virus;    Co-infection;    SRV;   

DOI  :  10.1590/S0037-86822010000500030

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

A report of a 67 year-old male patient with positive serology for HCV. PCR revealed the presence of HCV RNA, viral load of 2,000 copies/mL and genotypes 1 and 2. The pacient was treated with peginterferon alfa-2a at 180mcg/week and ribavirin at 1,000mg/day. In week four of treatment, HCV viral load was undetectable. In week nine, the patient developed hematemesis, worsening of asthenia, anorexia and impaired general condition, so the treatment was discontinued. The PCR was negative six months and one year after the cessation of treatment. The patient remains asymptomatic.

【 授权许可】

Unknown