Anorrectal lesions in HIV-positive patients using highly active antiretroviral therapy

Revista da Sociedade Brasileira de Medicina Tropical

Hospital Universitário de Brasília, Brasília¹  Universidade de Brasília, Brasília¹  Retamozo-Palacios, Manuel¹  Santos, João Barberino¹  Sousa, João Batista de¹ 

关键词: HIV;    AIDS;    Anorectal lesions;    HAART;   

DOI  :  10.1590/S0037-86822007000300007

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Anorectal lesions are common in patients with human immunodeficiency virus (HIV). Highly active anti-retroviral therapy (HAART) has little influence on the progression of anal neoplasms. The prevalence of anorectal lesions in 88 HIV-positive patients attended at the infectious diseases service of the University Hospital of Brasília who were using HAART was studied. Sociodemographic data were collected using a pre-prepared questionnaire and then the patients underwent proctological examination. Around 71% of the patients said they practiced anal intercourse. 30.7% were using a protease inhibitor. The prevalence of anorectal lesions was 36.4%, and condyloma acuminata and anal fissure were the most frequent of these. Condyloma acuminata was the most prevalent anorectal lesion and was strongly associated with the use of lopinavir/ritonavir. Screening for anorectal lesions caused by human papillomavirus in HIV/AIDS patients who use protease inhibitors is suggested.

【 授权许可】

Unknown