Investigation of enterovirus in cases of aseptic meningitis syndrome of Belém, PA

Revista da Sociedade Brasileira de Medicina Tropical

Gomes, Maria de Lourdes Contente¹  Lamarão, Letícia Martins¹  Fonseca, Cleide Mara¹  Araújo, Lia C.B.¹  Ferreira, Lauze Lee Alves¹  Santana, Marquete B.¹  Universidade Federal do Pará, Belém¹  Instituto Evandro Chagas, Belém¹  Secretaria-executiva de Estado da Saúde do Pará, Belém, PA¹  Universidade Federal da Bahia, Salvador¹  Tavares-Neto, José¹ 

关键词: Enterovirus;    Aseptic meningitis;    Cerebrospinal fluid;   

DOI  :  10.1590/S0037-86822005000500005

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

With the objective of isolating and identifying enteroviral serotypes, which are the most frequent etiologic agents of aseptic meningitis syndrome, cerebrospinal fluid samples were studied from patients referred to the health unit in the City of Belém (State of Pará, Brazil), from March 2002 to March 2003. The samples were inoculated in RD and HEp-2 cells line, and the positive were identified by neutralization test or indirect immunofluorescence. Out of 249 samples, 33 (13.2%) were positive 57.6% (n = 19) in patients under 11 years of age (p <0.03) and predominantly (72.7%) in males (p <0.008). The serotypes isolated were: Echovirus 30 (n = 31), Coxsackievirus B5 (n = 1) and Echovirus 30 and 4. In conclusion, this type of study also serves to determine the national picture, which is still little defined, regarding the most prevalent viral agents in AMS cases.

【 授权许可】

Unknown