Seroprevalence of hepatitis B virus infection and seroconvertion to anti-HBsAg in laboratory staff in Goiânia, Goiás

Revista da Sociedade Brasileira de Medicina Tropical

Fiaccadori, Fabíola Souza¹  Cardoso, Divina das Dores de Paula¹  Martins, Regina Maria Bringel¹  Daher, Roberto Ruhman¹  Universidade Federal de Goiás, Goiânia¹  Silva, Paula Andréia¹  Borges, Ana Maria Tavares¹  Silva, Simone Almeida¹ 

关键词: Hepatitis B;    Seroprevalence;    Vaccination;    Laboratory staff;   

DOI  :  10.1590/S0037-86822005000200005

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Were analyzed 648 serum samples from laboratory staff in Goiânia, Goiás aiming detection of three serological markers of HBV: HBsAg, anti-HBsAg and anti-HBcAg. The HBsAg and anti-HBcAg positive samples were also analyzed for HBeAg, anti-HBeAg and anti-HBcAgIgM markers. HBV infection rate of 24.1% was observed and, from them, 0.7% were positive for HBsAg. Viral DNA was detected by PCR in two HBsAg positive samples. A vaccination index of 74.5% and a global index of 89.9% of serological response to vaccination were observed. The direct work with biological fluids as well as cleaning workers represented significant risks for acquisition of HBV infection. The data from the present study showed an increase of the vaccination index among laboratory staff but the rates of HBV infection did not change through the years in the region.

【 授权许可】

Unknown